FLOT2 and SPATA24

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		FLOT2	SPATA24
Description		flotillin 2	spermatogenesis associated 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Uropod Acrosomal Membrane Endosome Plasma Membrane Caveola Adherens Junction Focal Adhesion Membrane Basolateral Plasma Membrane Apical Plasma Membrane Flotillin Complex Lamellipodium Endocytic Vesicle Cortical Actin Cytoskeleton Cytoplasmic Vesicle Vesicle Dendrite Cytoplasm Intracellular Membrane-bounded Organelle Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Extracellular Exosome Glutamatergic Synapse Anchored Component Of Presynaptic Active Zone Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protease Binding Protein Binding Ionotropic Glutamate Receptor Binding	DNA Binding Protein Binding
	Biological Process	Membrane Raft Assembly Cell Adhesion Epidermis Development Negative Regulation Of Gene Expression Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Toll-like Receptor 3 Signaling Pathway Protein Localization To Plasma Membrane Raft Regulation Of Myoblast Differentiation Protein Stabilization Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Plasma Membrane Anterograde Dendritic Transport Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Establishment Of T Cell Polarity	Spermatogenesis Cell Differentiation
Pathways		RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RND3 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Declining hemoglobin trajectory in blood donors ( 33491795) Mean corpuscular hemoglobin ( 29403010) Red blood cell count ( 27863252)	Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)
Interacting Genes		11 interacting genes: APP CAV1 CAV2 DXO FLOT1 FYN HGS MAGEB4 NMNAT1 SPATA24 UBC	24 interacting genes: CALCOCO2 CAMK2D CEP72 CTNNBIP1 CYSRT1 EFEMP2 EHD2 FLOT2 KDM1A KRT31 KRT40 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP4-2 LZTS2 MDFI MID2 NBPF19 NOTCH2NLA OIP5 PLEKHF2 PTAFR SUV39H1
Entrez ID		2319	202051
HPRD ID		00580	19510
Ensembl ID		ENSG00000132589	ENSG00000170469
Uniprot IDs		A0A024QZ62 J3QLD9 Q14254 Q6FG43 Q9BTI6	Q86W54
PDB IDs
Enriched GO Terms of Interacting Partners?
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