TAB2 and CST9L

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TAB2	CST9L
Description		TGF-beta activated kinase 1 (MAP3K7) binding protein 2	cystatin 9 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Endosome Membrane	Extracellular Space
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Cysteine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Heart Development Negative Regulation Of Autophagy Response To Lipopolysaccharide Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Kinase Activity	Negative Regulation Of Endopeptidase Activity Antimicrobial Humoral Response
Pathways		Nuclear signaling by ERBB4 Nuclear signaling by ERBB4 NOD1/2 Signaling Pathway Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS		Breast cancer ( 22383897 29059683) Coronary artery disease ( 33020668) Diverticulitis ( 28585551) Dupuytren's disease ( 28886342 21732829) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172)	Cystatin C levels ( 17903292)
Interacting Genes		43 interacting genes: APP CAMK2A CST9L EIF2AK2 EMILIN1 ERBB4 FN1 FOSL1 GTF2I HDAC1 HDAC3 HDAC5 HSF2BP IKBKB IKBKG IRAK1 KRT85 MAP3K7 NCOR1 NFKB1 NR2C2 NUMBL PPIL3 PPP2CB SLC19A3 TAB1 TBL1X TGM2 TNFRSF11A TPM3 TRAF2 TRAF3IP1 TRAF6 TTN UBC UBE2I VIM VPS52 XIAP YWHAZ ZBTB16 ZFP64 ZNF143	10 interacting genes: CCR5 CYSRT1 KRTAP10-3 KRTAP10-9 KRTAP5-1 MEI4 NBPF19 NOTCH2NLA SLC22A2 TAB2
Entrez ID		23118	128821
HPRD ID		05483	16769
Ensembl ID		ENSG00000055208	ENSG00000101435
Uniprot IDs		B4DIR9 Q9NYJ8	A0A140VJH1 Q9H4G1
PDB IDs		2DAE 2WWZ 2WX0 2WX1
Enriched GO Terms of Interacting Partners?
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