FNBP1 and RND2

Number of citations of the paper that reports this interaction (PubMedID 12244061)
24

Data Source:
HPRD (in vitro, two hybrid)

		FNBP1	RND2
Description		formin binding protein 1	Rho family GTPase 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Acrosomal Membrane Early Endosome Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Protein N-terminus Binding
	Biological Process	Endocytosis Signal Transduction	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Collateral Sprouting
Pathways		Clathrin-mediated endocytosis CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RND2 GTPase cycle	RND2 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688) Physiological dysregulation (Mahalanobis distance) ( 32235003)	Coronary artery disease ( 29212778)
Interacting Genes		13 interacting genes: AGTR1 AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	7 interacting genes: ARHGAP5 FNBP1 MEOX2 RACGAP1 TUBG1 UBXN11 VPS4A
Entrez ID		23048	8153
HPRD ID		10446	03332
Ensembl ID		ENSG00000187239	ENSG00000108830
Uniprot IDs		B7ZL13 B7ZL14 Q96RU3	P52198
PDB IDs		2EFL
Enriched GO Terms of Interacting Partners?
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