MAPKBP1 and ALG13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MAPKBP1	ALG13
Description		mitogen-activated protein kinase binding protein 1	ALG13 UDP-N-acetylglucosaminyltransferase subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitotic Spindle Pole	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	RNA Binding N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Thiol-dependent Deubiquitinase
	Biological Process	Negative Regulation Of Interleukin-8 Production Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Defense Response To Bacterium	Proteolysis
Pathways			Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Drugs
Diseases
GWAS		Body shape index ( 34021172) Diastolic blood pressure ( 27841878) Urinary albumin excretion ( 30220432) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Rosacea symptom severity ( 29771307) Shoulder impingement or rotator cuff tear ( 33482370)
Interacting Genes		64 interacting genes: ADAM12 ADAMTSL4 ALG13 APTX CTDSP1 CYSRT1 FOXN1 FXR1 FXR2 GLRX3 HOXA1 KEAP1 KPRP KRT31 KRT34 KRT35 KRT38 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 MAPK10 MAPK8 MAPK9 MDFI MEOX2 METTL15 MYOG NBPF19 NOTCH2NLA PLA2G10 PLSCR3 RBCK1 RGS20 SIAH1 SPRY2 SPRY3 TCF12 TCF4 TEKT5 TEX11 TRIM27 TRIM42 TRIP6 YPEL5 ZNF34	11 interacting genes: ATN1 ATXN1L BAG4 HOXA1 MAPKBP1 PITX1 RBFOX1 RERE RHOU ROR2 TRIM14
Entrez ID		23005	79868
HPRD ID		17465	06542
Ensembl ID		ENSG00000137802	ENSG00000101901
Uniprot IDs		O60336	A0A087WT15 A0A087WX43 Q9NP73
PDB IDs
Enriched GO Terms of Interacting Partners?
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