TRIM32 and SCGB1A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM32	SCGB1A1
Description		tripartite motif containing 32	secretoglobin family 1A member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament	Extracellular Space Nuclear Envelope Cytoplasm Rough Endoplasmic Reticulum Secretory Granule Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Identical Protein Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity	Protein Binding Phospholipase A2 Inhibitor Activity Polychlorinated Biphenyl Binding
	Biological Process	Protein Polyubiquitination Tissue Homeostasis Ubiquitin-dependent Protein Catabolic Process Actin Ubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Muscle Cell Cellular Homeostasis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Striated Muscle Cell Differentiation Axon Development Protein K48-linked Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cell Motility	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Female Pregnancy Embryo Implantation Response To Xenobiotic Stimulus Response To Ozone Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Response To Silicon Dioxide Response To Cytokine Negative Regulation Of T Cell Proliferation Negative Regulation Of Catalytic Activity Regulation Of MRNA Stability Regulation Of Inflammatory Response Response To Glucocorticoid Response To Fibroblast Growth Factor
Pathways		Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation
Drugs			4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Hip circumference adjusted for BMI ( 34021172)	Alanine aminotransferase levels ( 33547301) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Gamma glutamyl transferase levels ( 29403010) Serum CC16 levels ( 32839289) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		70 interacting genes: ABI2 AKTIP APOL1 ASIC4 ASTN2 ATP2B1 ATXN1 CLIP4 DERL1 ERGIC3 FADS6 GABARAP GABARAPL1 GABARAPL2 GEM GLIS2 GPR137B GSN HSPA4 ICMT IQCB1 IRAK1 KCTD9 LCN2 MAP1LC3A MAP1LC3B MAP1LC3C MID2 MOB1A MYCN NDRG2 NPAS3 NTAQ1 PDE9A PELI2 PIAS3 PIAS4 POLE3 PTCD2 PTPN11 RAB29 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP STING1 SYT6 TCEANC TNC TOP1 TRIM23 TRIM27 TRIM5 TRIM72 TTC23 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2V1 UBQLN1 UBQLN4 VPS11 XIAP	9 interacting genes: AQP6 CUBN FN1 LMBR1L LRP2 MARK2 STARD3 TMEM43 TRIM32
Entrez ID		22954	7356
HPRD ID		03797	01884
Ensembl ID		ENSG00000119401	ENSG00000149021
Uniprot IDs		A0A024R843 Q13049	A0A0S2Z4R6 P11684
PDB IDs		2CT2 5FEY
Enriched GO Terms of Interacting Partners?
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