SEPHS1 and GBP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SEPHS1	GBP2
Description		selenophosphate synthetase 1	guanylate binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Nuclear Membrane	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Selenide, Water Dikinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cellular Protein Modification Process Selenocysteine Biosynthetic Process Phosphorylation	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways			Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Metabolite levels ( 23823483) Schizophrenia x sex interaction ( 34099189)	Serum metabolite levels ( 33031748)
Interacting Genes		18 interacting genes: CDCA4 CRMP1 DEPDC7 ERG28 GBP2 IGSF21 PLAGL2 QRICH1 SAT1 SLC35F6 SPACA9 UNC119 XAF1 ZBTB25 ZNF202 ZNF276 ZNF474 ZNF526	23 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LRRC8B LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG
Entrez ID		22929	2634
HPRD ID		02944	02682
Ensembl ID		ENSG00000086475	ENSG00000162645
Uniprot IDs		P49903	P32456 Q8TCE5
PDB IDs		3FD5 3FD6	6VKJ
Enriched GO Terms of Interacting Partners?
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