HABP4 and TOPORS

Number of citations of the paper that reports this interaction (PubMedID 16455055)
10

Data Source:
HPRD (two hybrid)

		HABP4	TOPORS
Description		hyaluronan binding protein 4	TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Stress Granule Cajal Body Sarcoplasm Nuclear Speck Sarcomere Gemini Of Coiled Bodies	Ubiquitin Ligase Complex Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Centriole PML Body Nuclear Speck Midbody Photoreceptor Connecting Cilium Ciliary Basal Body
	Molecular Function	RNA Binding Protein Binding SUMO Binding	DNA Binding Antigen Binding Ubiquitin-protein Transferase Activity Protein Binding SUMO Transferase Activity DNA Topoisomerase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Processing RNA Splicing PML Body Organization Positive Regulation Of RNA Splicing Negative Regulation Of DNA Binding Positive Regulation Of Translational Initiation Cellular Response To Mechanical Stimulus	Protein Polyubiquitination Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Retina Layer Formation Protein Sumoylation Protein Localization To Nucleus Photoreceptor Cell Outer Segment Organization Regulation Of Cell Population Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Retinal Rod Cell Development Retinal Cone Cell Development Positive Regulation Of Ubiquitin-protein Transferase Activity Maintenance Of Protein Location In Nucleus Protein K48-linked Ubiquitination
Pathways		Platelet degranulation	SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of immune response proteins
Drugs		Hyaluronic acid
Diseases
GWAS		Height ( 25282103 31562340) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Waist circumference adjusted for body mass index ( 34021172)	Early spontaneous preterm birth ( 31194736) Immune response to smallpox vaccine (IL-6) ( 22610502) Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: C1QBP CHD3 CRK DAXX ENO2 FRA10AC1 HMGXB4 KAT5 OGT PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 RACK1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1	28 interacting genes: CASP8 CREBBP EPM2A H2AX HABP4 MTDH NKX3-1 SATB1 SERBP1 SIN3A SNIP1 SPOP SUMO1 SUMO2 TOP1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2J1 UBE2L6 UBE2N UBE2W XRCC1
Entrez ID		22927	10210
HPRD ID		13628	11642
Ensembl ID		ENSG00000130956	ENSG00000197579
Uniprot IDs		Q5JVS0	Q9NS56
PDB IDs
Enriched GO Terms of Interacting Partners?
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