NCBP2 and DDX39B

Number of citations of the paper that reports this interaction (PubMedID 17190602)
214

Data Source:
BioGRID (pull down)

		NCBP2	DDX39B
Description		nuclear cap binding protein subunit 2	DExD-box helicase 39B
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol MRNA Cap Binding Complex Nuclear Cap Binding Complex RNA Cap Binding Complex	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding SnRNA Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA ATP Hydrolysis Activity U6 SnRNA Binding U4 SnRNA Binding Identical Protein Binding ATP-dependent Protein Binding Protein-containing Complex Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome SnRNA Export From Nucleus Regulation Of Translational Initiation RNA Splicing Gene Silencing By RNA Positive Regulation Of MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of RNA Export From Nucleus MRNA Transport Pre-mRNA Cleavage Required For Polyadenylation Regulation Of MRNA Polyadenylation	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Liver Development RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Translation Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of DNA Biosynthetic Process
Pathways		SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Abortive elongation of HIV-1 transcript in the absence of Tat snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Signaling by FGFR2 IIIa TM Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination RHOBTB2 GTPase cycle
Drugs			Artenimol
Diseases
GWAS		Malaria ( 31844061) Night sleep phenotypes ( 27126917) Pre-treatment viral load in HIV-1 infection ( 31219150)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Mean platelet volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 27863252) Mosquito bite size ( 28199695) Myositis ( 26291516) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		7 interacting genes: DDX39B EIF4G1 EIF5 HNRNPF HNRNPH1 LZTS2 NCBP1	31 interacting genes: ALYREF BARD1 CHTOP DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R LUZP4 NCBP2 OGT PIAS2 RBM39 RNF4 RPS15A SARNP SDCBP SNRPA SREK1 SRPK2 STRN4 TDG THOC3 THOC6 TUBB3 U2AF2 UBE2I YWHAG ZHX1
Entrez ID		22916	7919
HPRD ID		05503	00805
Ensembl ID		ENSG00000114503	ENSG00000198563
Uniprot IDs		B3KSB0 P52298	A0A024RCM3 Q13838
PDB IDs		1H2T 1H2U 1H2V 1H6K 1N52 1N54 3FEX 3FEY 5OO6 5OOB 6D0Y 7ABG	1T5I 1T6N 1XTI 1XTJ 1XTK 7APK
Enriched GO Terms of Interacting Partners?
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