ALDOB and AGXT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ALDOB	AGXT2
Description		aldolase, fructose-bisphosphate B	alanine--glyoxylate aminotransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	Alanine-glyoxylate Transaminase Activity Pyridoxal Phosphate Binding (R)-3-amino-2-methylpropionate-pyruvate Transaminase Activity
	Biological Process	Fructose Metabolic Process Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Vacuolar Proton-transporting V-type ATPase Complex Assembly	Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-alanine Catabolic Process, By Transamination Positive Regulation Of Nitric Oxide Biosynthetic Process
Pathways		Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism	Glyoxylate metabolism and glycine degradation Pyrimidine catabolism
Drugs		1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate	Pyridoxal phosphate Pyruvic acid Glycine Alanine
Diseases
GWAS		Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Serum alkaline phosphatase levels ( 33547301 29403010 33339817)	Metabolite levels ( 21931564) Serum dimethylarginine levels (asymmetric/symetric ratio) ( 24159190) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 33031748) Symmetrical dimethylarginine levels ( 25245031 24159190) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407 21572414) Urinary metabolites (H-NMR features) ( 24586186)
Interacting Genes		22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2	2 interacting genes: ALDOB CYP2E1
Entrez ID		229	64902
HPRD ID		01972	10638
Ensembl ID		ENSG00000136872	ENSG00000113492
Uniprot IDs		A0A024R145 P05062	Q9BYV1
PDB IDs		1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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