KHDC4 and KCNIP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KHDC4	KCNIP3
Description		KH domain containing 4, pre-mRNA splicing factor	potassium voltage-gated channel interacting protein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Protein-DNA Complex Axon Terminus
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding
	Biological Process	MRNA Splice Site Selection	Negative Regulation Of Transcription By RNA Polymerase II Intracellular Protein Transport Apoptotic Process Signal Transduction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport
Pathways			Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS			Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		21 interacting genes: BANP C14orf119 DNAJC5 KCNIP3 MAGEA12 NRF1 NUTF2 PIDD1 PRKAB2 PRR13 PSMB1 PUF60 QRICH1 RBM23 RBM39 RHOXF2 SAT1 SPANXN2 U2AF2 ZDHHC17 ZRSR2	27 interacting genes: ASPH C1QTNF2 CALM2 CASP3 CD177 CDSN CFLAR CLN3 CREB1 CREM CTBP2 GOLGA7 GRK2 GRK6 IGF1R IGLV3-25 IL6ST KHDC4 MAVS PCBD2 PPP3CA PSEN1 PSEN2 SOD3 SRL TARBP2 ZG16
Entrez ID		22889	30818
HPRD ID		17198	05232
Ensembl ID		ENSG00000132680	ENSG00000115041
Uniprot IDs		Q7Z7F0	A0A024RE22 Q9Y2W7
PDB IDs		2YQR	2E6W
Enriched GO Terms of Interacting Partners?
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