ZHX2 and NFYA

Number of citations of the paper that reports this interaction (PubMedID 12741956)
39

Data Source:
HPRD (in vivo, two hybrid)

		ZHX2	NFYA
Description		zinc fingers and homeoboxes 2	nuclear transcription factor Y subunit alpha
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II MRNA Catabolic Process Somatic Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Negative Regulation Of Transcription, DNA-templated Retinal Bipolar Neuron Differentiation	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways			PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Carotid intima media thickness ( 30510157 21909108) Chin dimples ( 27182965) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494)	Mean spheric corpuscular volume ( 32888494) White blood cell count ( 27863252)
Interacting Genes		10 interacting genes: APP ATXN1 DHRS2 LAT NAGPA NFYA RAB7A YWHAQ ZHX1 ZHX3	50 interacting genes: APP APPBP2 ATF6 ATF6B ATXN1 BANP BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 DVL3 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NEU1 NFYB NFYC NOTCH4 NR5A1 PAPOLG POGZ POU2F1 POU3F2 PWP1 QRICH1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 UBL5 USF1 USF2 VEZF1 ZC3H10 ZHX1 ZHX2 ZHX3
Entrez ID		22882	4800
HPRD ID		16458	01793
Ensembl ID		ENSG00000178764	ENSG00000001167
Uniprot IDs		Q9Y6X8	A0A024RD22 P23511
PDB IDs		2DMP 3NAU	4AWL 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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