IKZF3 and NTAQ1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		IKZF3	NTAQ1
Description		IKAROS family zinc finger 3	N-terminal glutamine amidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Metal Ion Binding Promoter-specific Chromatin Binding	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Mesoderm Development Response To Bacterium Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Cellular Protein Modification Process
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 29348612) Asthma ( 31959851 31619474 28461288) Asthma (moderate or severe) ( 30552067) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Asthma with severe exacerbations ( 32841424) Atopic march ( 26542096) Bronchial hyperresponsiveness in asthma ( 27439200) Crohn's disease ( 28067908 21102463) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908 23128233) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Marginal zone lymphoma or systemic lupus erythematosus ( 31407831) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 30343302) Primary biliary cholangitis ( 19458352 23000144 20639880 26394269 28062665 30643196) Primary biliary cirrhosis ( 22961000) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 23143596 24390342 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Selective IgA deficiency ( 27723758) Self-reported allergy ( 23817569) Systemic lupus erythematosus ( 27399966 26502338) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 31672989) Type 1 diabetes ( 30659077 25751624) Ulcerative colitis ( 28067908 20228799 21297633)
Interacting Genes		166 interacting genes: ABLIM3 AKAP10 AKAP9 ANKS1A AQP1 ARMC7 ARNT2 ATP6V0D1 ATP6V0D2 ATPAF2 ATXN7L2 BCAS2 BCL2L1 BLK BLZF1 BYSL C1orf109 C1QL1 C2CD6 CABP4 CABP5 CARD9 CATSPER1 CCDC102B CCDC187 CCDC24 CCDC57 CCHCR1 CDC37 CDC7 CDK4 CDKN1A CDKN2D CFAP206 CHCHD2 CHD3 CKS1B CLCNKA COA3 CRBN CRK CRYBA4 DGCR6 DTX2 EFHC1 EGLN3 EMC2 ENKD1 EXOC8 EXOSC5 FAM124B FANCG FANCL FARS2 FBF1 FHL3 FRS3 GEM GOLGA2 GOLGA6A GRAP2 GRB2 HNRNPF HNRNPLL HOXC8 HRAS IKZF1 IKZF4 IKZF5 ING5 KANK2 KAT5 KIF9 KIFC3 KLHL38 KRT19 LDOC1 LENG1 LGALS14 LMO1 LMO2 LMO4 LNX1 LONRF1 MAD2L2 MAGOHB MCM7 MCRS1 MID2 MISP MKRN3 MORN3 MRPL28 MRPL53 MYO15B NATD1 NBR2 NEK6 NFKBID NME7 NOS3 NTAQ1 NUDT16L1 NXT2 OAZ3 OSBPL7 OSGIN1 PCID2 PDZD4 PFDN5 PIK3R1 PIK3R2 PIN1 POLM POLR1C PPP1R16B PPP1R18 PRAC1 PRDM1 PRKAA1 PRKAA2 PRKAB2 PSMA1 PSME3 PSMF1 RAD51D RBBP8 RCOR3 RHOA RNF6 RUNX1 SCNM1 SMARCB1 SMARCD1 SPG21 STAMBPL1 STK16 STK26 STX11 SUMO1 TBC1D22B TCAF1 TCAP TCEANC TCHP TEKT3 TEKT4 TFAP2D TLE5 TOB1 TRAPPC6A TRIM42 TSEN15 TSGA10IP TSSK3 TSTD2 TUBG2 UBE2I USP2 VAT1 VBP1 YES1 ZGPAT ZMYM2 ZNF587 ZNF76	380 interacting genes: - AARD ACD ACOT13 ACTB ACTG1 ACTN2 ACY1 ADAMTSL4 AGR2 AGR3 AIMP2 AKIRIN2 AMOT AMOTL2 AMPD2 ANKRD11 ANKRD36B AOC1 APIP ARID4B ARL6IP1 ASL ATP6V1G1 BANF2 BCL2L2-PABPN1 BEND5 BIRC7 BLMH BLOC1S6 BLZF1 BOLA2 BOLA2B BORCS6 BPIFB3 BTBD1 BTBD2 BTBD6 C1orf50 CAMK2A CAPN3 CARD9 CASP6 CAVIN4 CBFA2T2 CBS CBY2 CCDC102B CCDC115 CCDC152 CCDC184 CCDC197 CCHCR1 CCNB1IP1 CD22 CDA CDCA8 CDK2AP1 CDKN2AIPNL CDR2 CENPP CEP170B CEP55 CEP70 CEP85 CGGBP1 CHCHD3 CHMP4A CMTM5 COG6 COIL CRYAA CSNK2B CT45A1 CTAG1A CTAG1B CTBP1 CTH CUEDC1 CUTC CYSRT1 DAB1 DCTPP1 DEUP1 DHPS DNAL4 DNM2 DYNLT1 EDARADD EGLN3 EIF2B1 EIF4G1 EMILIN3 ENOX2 EP400 EPN3 ETV6 EXOSC8 FAM136A FAM72A FAM72D FKBP6 FTH1 FTL GADD45GIP1 GAS7 GCSAML GFAP GMCL1 GMDS GNG3 GNMT GNPDA2 GOLGA2 GOLGA6L9 GPX7 GRAMD4 GSTA4 GSTO2 GTF2H2C H2AP HAUS8 HBQ1 HBZ HEATR5A HGD HIGD1C HMG20A HOMER3 HOXB6 HPRT1 HSD17B14 HSF2BP HSPE1 HUS1 IKZF3 IL16 IL31 INCA1 ISCA2 ITGB3BP JAKMIP2 JUP KASH5 KATNBL1 KCNH1 KCTD1 KCTD10 KCTD13 KCTD15 KCTD21 KCTD4 KCTD6 KCTD7 KCTD9 KEAP1 KIF21B KLHL12 KLHL2 KLHL20 KRT27 KRT31 KRTAP10-5 KRTAP10-7 KRTAP19-2 KRTAP19-6 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-1 KRTAP9-2 KRTAP9-4 KRTAP9-8 L3MBTL3 LCE1C LCE1D LCE1E LCE1F LCE2C LCE5A LDB2 LENG1 LGALS2 LGALS9B LIN7B LMNA LMO1 LMO2 LMO3 LNX2 LONRF1 LRIF1 LRRC73 LSM12 LSM14B LZTFL1 LZTS1 LZTS2 MAB21L3 MAD1L1 MAGEA11 MAGEA12 MAGEA2 MAGEA2B MALSU1 MARCHF10 MATN4 MDFI MED22 MIF MIF4GD MIOS MIPOL1 MIS18A MITD1 MOB2 MORN3 MPLKIP MRFAP1L1 MRPL12 MTHFD2L MTUS2 MVP MXRA8 MYD88 N4BP3 NAB2 NADSYN1 NAGK NCOA5 NDUFAB1 NECAB2 NME1 NPL NR5A1 NT5C1A NTAN1 NUDT14 NUDT16L1 NUDT21 OOEP PAK5 PCBD1 PFDN5 PGPEP1 PIH1D2 PLA2G10 PLCD1 PLEKHB2 PLEKHJ1 PNMA1 PNMA2 PNMA5 POLR2J POMC PPCDC PPM1K PPP1R27 PRKAR1B PRMT1 PRMT5 PRPS2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRTFDC1 PSMB5 PSME3 PTS PYCR3 PYGM RAB42 RABAC1 RASAL3 RBBP8 RBM20 RBM45 RBM48 RBPMS RD3 REEP6 RHOQ RILPL1 RNF138 RNF4 ROPN1 RPIA RUSC1 S100A11 SAP18 SARS2 SAT1 SCARA5 SELENOV SEPTIN14 SEPTIN3 SFN SH3GLB2 SIAH1 SIKE1 SIVA1 SLAIN1 SLC15A2 SLPI SMAP1 SMN1 SNAP29 SNRPD3 SPANXB1 SPATA32 SPDYE4 SPINDOC SPRYD7 SSNA1 SSX2IP STH STMN2 STN1 STX11 SYCE1L SYNGAP1 TAX1BP1 TBX15 TCL1A TCP10L TEKT1 TEPSIN THAP1 THAP6 THAP7 THG1L TICAM2 TIFA TLE5 TMEM239 TNFAIP1 TNIP3 TNR TOLLIP TRAF1 TRAF3 TRAF5 TRIM23 TRIM27 TRIM32 TRIM5 TRIM54 TRIM69 TRIM73 TRIM9 TRIP13 TSC22D1 TSN TSNAX UBR1 UBR2 UFC1 UNKL VAC14 VCP VDR VPS37C VXN XIAP ZBED1 ZBTB8A ZBTB8B ZC2HC1C ZCCHC17 ZNF165 ZNF341 ZNF436 ZNF511 ZNF618 ZSCAN16 ZSCAN32
Entrez ID		22806	55093
HPRD ID		05869	07653
Ensembl ID		ENSG00000161405	ENSG00000156795
Uniprot IDs		Q9UKT9	A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8
PDB IDs			3C9Q 4W79 6KGJ
Enriched GO Terms of Interacting Partners?
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