ALDOA and BCAT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ALDOA	BCAT2
Description		aldolase, fructose-bisphosphate A	branched chain amino acid transaminase 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding	Branched-chain-amino-acid Transaminase Activity L-leucine:2-oxoglutarate Aminotransferase Activity L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity
	Biological Process	Fructose Metabolic Process Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Muscle Cell Cellular Homeostasis Protein Homotetramerization	Isoleucine Catabolic Process Branched-chain Amino Acid Biosynthetic Process Leucine Biosynthetic Process Valine Biosynthetic Process Regulation Of Hormone Levels Cellular Response To Leukemia Inhibitory Factor
Pathways		Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Branched-chain amino acid catabolism
Drugs		Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Pyridoxal phosphate Glutamic acid Leucine Isoleucine Pyridoxamine-5'-Phosphate N-[O-Phosphono-Pyridoxyl]-Isoleucine alpha-Ketoisovalerate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cataracts ( 34127677) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Long-term memory (delayed word recall task) ( 29970928) Resting metabolic rate ( 28476931) Serum metabolite levels ( 33031748)
Interacting Genes		35 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR ENO1 ENO3 ERBB2 ERBB3 ERBB4 FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 LINC01554 MLH1 MYOC OGT PCNA PIAS4 PLD2 SHANK3 SLC22A1 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1	4 interacting genes: ALDOA APP CREB3 PTGDS
Entrez ID		226	587
HPRD ID		00070	00217
Ensembl ID		ENSG00000149925	ENSG00000105552
Uniprot IDs		P04075 V9HWN7	B3KSI3 O15382
PDB IDs		1ALD 2ALD 4ALD 5KY6	1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HGX 2HHF 5BWR 5BWT 5BWU 5BWV 5BWW 5BWX 5CR5 5HNE 5I5S 5I5T 5I5U 5I5V 5I5W 5I5X 5I5Y 5I60 5MPR 6PRX
Enriched GO Terms of Interacting Partners?
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