FGF14 and SMC1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FGF14	SMC1A
Description		fibroblast growth factor 14	structural maintenance of chromosomes 1A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Mitotic Spindle Pole
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity	DNA Binding Chromatin Binding RNA Binding Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity
	Biological Process	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity	Mitotic Sister Chromatid Segregation DNA Repair Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Response To Radiation Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Response To DNA Damage Checkpoint Signaling Mitotic Spindle Assembly
Pathways		Phase 0 - rapid depolarisation	Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Bipolar disorder ( 31043756) Mean corpuscular volume ( 32888494)
Interacting Genes		13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA	21 interacting genes: ALK AMOT ATM BLM BRCA1 ESR1 FGF14 MCM6 MCM7 MDC1 MET MSH2 MSH6 NDC80 NUMA1 POLA1 RAD21 RFC1 RPGR SMC3 SUMO2
Entrez ID		2259	8243
HPRD ID		03305	02077
Ensembl ID		ENSG00000102466	ENSG00000072501
Uniprot IDs		Q92915	A0A384MR33 G8JLG1 Q14683 Q68EN4
PDB IDs			6WG3 6WG4 6WG6 6WGE
Enriched GO Terms of Interacting Partners?
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