FERD3L and TWIST2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FERD3L	TWIST2
Description		Fer3 like bHLH transcription factor	twist family bHLH transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Developmental Process Floor Plate Development Negative Regulation Of Transcription, DNA-templated Cell Development Regulation Of Neurogenesis	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Cell Migration Developmental Process Negative Regulation Of Apoptotic Process Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways			Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549) Height ( 31562340) Obesity-related traits ( 23251661) Refractive error ( 32231278) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Blond vs. brown/black hair color ( 30531825) Chronic obstructive pulmonary disease ( 30804561) Male-pattern baldness ( 29146897 27182965 28196072) Morning person ( 30696823) Pancreas volume ( 34128465) Rosacea symptom severity ( 29771307) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		10 interacting genes: CTNNA3 FAM9B MAGEB4 MSGN1 SGTA TCF12 TCF3 TCF4 TMBIM6 TWIST2	9 interacting genes: CRK FERD3L GLIS2 MEF2C PLCG2 SREBF1 TCF12 TCF3 TCF4
Entrez ID		222894	117581
HPRD ID		16890	09616
Ensembl ID		ENSG00000146618	ENSG00000233608
Uniprot IDs		Q96RJ6	A1MB48 Q8WVJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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