ZSCAN23 and LHPP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZSCAN23	LHPP
Description		zinc finger and SCAN domain containing 23	phospholysine phosphohistidine inorganic pyrophosphate phosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytosol Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Inorganic Diphosphatase Activity Protein Binding Phosphatase Activity Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Phosphate-containing Compound Metabolic Process Dephosphorylation
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Fish- and plant-related diet ( 32066663) Liver iron content ( 34128465) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 28991256) Subcortical volume (MOSTest) ( 32665545)	Acute lymphoblastic leukemia (childhood) ( 29348612) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299 27694927) Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065) Asthma ( 27611488) B-cell acute lymphoblastic leukaemia ( 31767839) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal tail volume ( 30279459) Iron status biomarkers (ferritin levels) ( 28334935) Male-pattern baldness ( 28196072) Obesity-related traits ( 23251661) Risky sexual behaviors (alcohol dependence interaction) ( 27531626) Serum metabolite levels ( 33031748) Subcutaneous adipose tissue ( 22589738) Testicular germ cell tumor ( 28604732) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		22 interacting genes: BICD2 CDR2L CEP70 DDIT4L GOLGA6L9 LHPP PCDHB12 PICK1 PPARA PRKAA2 SCAND1 SDCBP TRAF2 TULP3 YJU2B ZKSCAN7 ZNF24 ZNF426 ZNF446 ZSCAN21 ZSCAN22 ZSCAN9	1 interacting genes: ZSCAN23
Entrez ID		222696	64077
HPRD ID		19514	17274
Ensembl ID		ENSG00000187987	ENSG00000107902
Uniprot IDs		Q3MJ62	Q5T1Z0 Q9H008
PDB IDs			2X4D
Enriched GO Terms of Interacting Partners?
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