MTURN and TRIM38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MTURN	TRIM38
Description		maturin, neural progenitor differentiation regulator homolog	tripartite motif containing 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cellular_component Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of ERK1 And ERK2 Cascade	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Cadmium levels ( 26025379)	Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cardiac hypertrophy ( 21348951) Fish- and plant-related diet ( 32066663) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		23 interacting genes: AP2M1 APP ARRDC1 DAZAP2 MKRN1 PLEKHB2 REL RNF41 RPS27A SH3RF1 SSX1 SUSD6 TMEM239 TNFRSF19 TP53BP2 TRAF6 TRIM38 TRIM39 TRIM5 TRIM8 UBA52 UBB UBC	34 interacting genes: ATXN1 BYSL EIF1B GMCL1 GORASP2 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 MTMR6 MTURN PIAS4 PSMA4 RFC5 RIPK1 RNF4 SDCBP SOX2 SPTLC1 STXBP1 TCEA2 TSBP1 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U ZNF764
Entrez ID		222166	10475
HPRD ID		07635	15555
Ensembl ID		ENSG00000180354	ENSG00000112343
Uniprot IDs		Q8N3F0	A0A024QZY4 O00635
PDB IDs
Enriched GO Terms of Interacting Partners?
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