SP8 and ZNF273

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		SP8	ZNF273
Description		Sp8 transcription factor	zinc finger protein 273
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Embryonic Limb Morphogenesis	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Asthma ( 31959851) Bipolar I disorder ( 20386566) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Prostate cancer ( 23535732) Response to statin therapy ( 20339536) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alzheimer disease and age of onset ( 26830138) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		3 interacting genes: HEYL ZNF273 ZNF519	3 interacting genes: CA14 KRTAP10-5 SP8
Entrez ID		221833	10793
HPRD ID		12208	07264
Ensembl ID		ENSG00000164651	ENSG00000198039
Uniprot IDs		A8K350 Q8IXZ3	Q14593
PDB IDs
Enriched GO Terms of Interacting Partners?
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