FCGRT and CLDN19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCGRT	CLDN19
Description		Fc fragment of IgG receptor and transporter	claudin 19
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding IgG Binding Beta-2-microglobulin Binding Peptide Antigen Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	IgG Immunoglobulin Transcytosis In Epithelial Cells Mediated By FcRn Immunoglobulin Receptor Immune Response	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 29403010) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum albumin level ( 23022100 29403010) Serum total protein level ( 23022100) Total cholesterol levels ( 29403010) Triglyceride levels ( 32203549)
Interacting Genes		9 interacting genes: ALB B2M CA6 CLDN19 FAM3C MTDH NINJ2 PMP22 UPK2	63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14
Entrez ID		2217	149461
HPRD ID		03257	10834
Ensembl ID		ENSG00000104870	ENSG00000164007
Uniprot IDs		A0A024QZI2 P55899	Q8N6F1
PDB IDs		1EXU 3M17 3M1B 4K71 4N0F 4N0U 5BJT 5BXF 5WHK 6C97 6C98 6C99 6FGB 6ILM 6LA6 6LA7 6NHA 6QIO 6QIP 7C9V
Enriched GO Terms of Interacting Partners?
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