FAM124A and PRKG1

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid)

FAM124A

PRKG1

Description family with sequence similarity 124 member A protein kinase cGMP-dependent 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Adult body size ( 32376654)
  • Alcohol misuse (trauma interaction) ( 28265120)
  • Anti-chlamydia trachomatis IgG seropositivity ( 29967566)
  • Arthritis (juvenile idiopathic) ( 34101054)
  • Asthma ( 21907864)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778)
  • Gait rhythm ( 26219847)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Height ( 28552196 31562340)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Logical memory (delayed recall) in normal cognition ( 29274321)
  • Loneliness (multivariate analysis) ( 27629369)
  • Mammographic density (non-dense area) ( 25342443)
  • Mitochondrial DNA copy number ( 30704525)
  • Obesity-related traits ( 23251661)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Stroke ( 32693751)
  • Systolic blood pressure ( 32902719)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 30 interacting genes: BEND7 CCDC33 CEP70 CGGBP1 DOCK8 FOXP2 IHO1 IL16 INO80E KIFC3 LNX1 NCK2 NKAP PHC2 PRKG1 RAB3IP RBM10 ROCK1 SAXO1 SRPK1 STAC3 THAP1 TLE5 TRIM41 TRIM54 ZBTB44 ZFP64 ZNF165 ZNF250 ZZZ3 39 interacting genes: ANXA7 AR ARHGEF15 CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 IRAG1 ITPR1 LASP1 LMO2 MEOX2 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RBAK RGS2 RYR1 SELL SEPTIN3 SF1 SPP1 TNNT1 TRIM39-RPP21 TRIM54 TRPC3 VASP WDR77 ZNF646
Entrez ID 220108 5592
HPRD ID 08704 08910
Ensembl ID ENSG00000150510 ENSG00000185532
Uniprot IDs Q86V42 Q13976
PDB IDs 1ZXA 3NMD 3OCP 3OD0 3OGJ 4KU7 4KU8 4QX5 4QXK 4R4L 4R4M 4Z07 5J48 5JAX 5JD7 5L0N 6BDL 6BG2 6C0T
Enriched GO Terms of Interacting Partners?
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Tagcloud (Intersection) ?