CYB561A3 and RNF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB561A3	RNF5
Description		cytochrome b561 family member A3	ring finger protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Iron Ion Homeostasis Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Response To Bacterium Negative Regulation Of Autophagy Ubiquitin-dependent ERAD Pathway Protein Destabilization ERAD Pathway Cellular Protein Catabolic Process Transmembrane Transport Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination ER-associated Misfolded Protein Catabolic Process Endoplasmic Reticulum Mannose Trimming Regulation Of Autophagosome Assembly
Pathways			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS			Advanced glycation end-product levels ( 26083729) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31	50 interacting genes: ABHD16A ARL6IP1 CFTR CYB561 CYB561A3 DGAT2L6 FAM241B FHOD1 GLP1R INSIG2 JKAMP LEPROTL1 MAVS MPDZ MS4A1 ORMDL3 PLP2 PLPP6 PRAF2 PXN RABAC1 RHBDD1 RUSF1 SCD SEC22A SLC1A1 SLC38A7 TGFBR1 TMEM120B TMEM242 TNFAIP3 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G2 UBE2K UBE2N UBE2U UBE2V1 UBE2W UBE2Z UBTD1 YIPF1 YIPF2 YIPF4
Entrez ID		220002	6048
HPRD ID		11316	04057
Ensembl ID		ENSG00000162144	ENSG00000204308
Uniprot IDs		F5H1Q2 Q8NBI2	A0A024RCQ4 Q99942
PDB IDs
Enriched GO Terms of Interacting Partners?
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