UNC5B and FLRT3

Number of citations of the paper that reports this interaction (PubMedID 21673655)
58

Data Source:
BioGRID (pull down, pull down)

		UNC5B	FLRT3
Description		unc-5 netrin receptor B	fibronectin leucine rich transmembrane protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Membrane Raft	Extracellular Space Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Cell Junction Extracellular Matrix Growth Cone Membrane Axon Terminus Axonal Growth Cone Synaptic Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane
	Molecular Function	Netrin Receptor Activity Protein Binding	Fibroblast Growth Factor Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Protein Homodimerization Activity Chemorepellent Activity
	Biological Process	Angiogenesis Apoptotic Process Axon Guidance Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Proepicardium Cell Migration Involved In Pericardium Morphogenesis Axon Guidance Synapse Assembly Heart Development Fibroblast Growth Factor Receptor Signaling Pathway Neuron Projection Development Embryonic Morphogenesis Response To Axon Injury Negative Chemotaxis Positive Regulation Of Synapse Assembly Head Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Synaptic Membrane Adhesion Neuron Projection Extension
Pathways		Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand	Signaling by ROBO receptors Downstream signaling of activated FGFR1
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 33772158) Diisocyanate-induced asthma ( 25918132) Problematic alcohol use ( 32451486) Vitiligo ( 22951725)	Bipolar disorder ( 33169155) Blood protein levels ( 30072576 29875488) Mood disorder in prion disease ( 25897833)
Interacting Genes		5 interacting genes: DAPK1 FLRT3 OIT3 PPP2R1B TREM2	3 interacting genes: FGFR1 IRF4 UNC5B
Entrez ID		219699	23767
HPRD ID		08487	05313
Ensembl ID		ENSG00000107731	ENSG00000125848
Uniprot IDs		Q8IZJ1	Q9NZU0
PDB IDs			5CMN 5CMP 6JBU
Enriched GO Terms of Interacting Partners?
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