PLAC9 and RNF213

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PLAC9	RNF213
Description		placenta associated 9	ring finger protein 213
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process		Angiogenesis Sprouting Angiogenesis Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Homooligomerization Protein Autoubiquitination Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			Suppression of apoptosis Signaling by ALK fusions and activated point mutants Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Aspartate aminotransferase levels ( 33547301) Coronary artery disease ( 33020668) Hypertension ( 32709000) Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Migraine ( 27182965 27322543) Moyamoya disease ( 21048783 29273593)
Interacting Genes		6 interacting genes: CCDC14 EMILIN1 GPRASP2 RAPGEF5 RNF213 SNAPIN	14 interacting genes: GOLGA2 KRT40 MTDH PLAC9 REL RPTOR SUMO2 TRIM23 TRIM27 TRIP6 UBE2D2 UBE2D3 UBE2L3 UBXN11
Entrez ID		219348	57674
HPRD ID		18491	10716
Ensembl ID		ENSG00000189129	ENSG00000173821
Uniprot IDs		Q5JTB5 Q5JTB6	A0A0A0MTC1 A0A0A0MTR7 Q63HN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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