FANCA and HPRT1

Number of citations of the paper that reports this interaction (PubMedID 14499622)
15

Data Source:
BioGRID (two hybrid)

		FANCA	HPRT1
Description		FA complementation group A	hypoxanthine phosphoribosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Identical Protein Binding Guanine Phosphoribosyltransferase Activity
	Biological Process	DNA Repair Male Meiotic Nuclear Division Male Gonad Development Female Gonad Development Interstrand Cross-link Repair Regulation Of Cell Population Proliferation Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Protein-containing Complex Assembly Regulation Of CD40 Signaling Pathway	T Cell Mediated Cytotoxicity Response To Amphetamine Purine Nucleotide Biosynthetic Process Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage Grooming Behavior Locomotory Behavior Striatum Development Cerebral Cortex Neuron Differentiation Central Nervous System Neuron Development GMP Salvage IMP Salvage Dopamine Metabolic Process Hypoxanthine Salvage AMP Salvage Positive Regulation Of Dopamine Metabolic Process GMP Catabolic Process IMP Metabolic Process Hypoxanthine Metabolic Process Lymphocyte Proliferation Dendrite Morphogenesis Protein Homotetramerization
Pathways		Fanconi Anemia Pathway	Purine salvage
Drugs			Mercaptopurine 5-O-phosphono-alpha-D-ribofuranosyl diphosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine 3H-pyrazolo[4,3-d]pyrimidin-7-ol 9-Deazaguanine
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hair morphology traits ( 30166351) Hemoglobin levels ( 32327693) Homocysteine levels ( 23824729) Intraocular pressure ( 29617998 29785010 31959993 30054594) Low tan response ( 29739929) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Skin pigmentation traits ( 30166351)	Estimated glomerular filtration rate ( 31015462)
Interacting Genes		47 interacting genes: AKT1 ALDOA ATP5F1B ATR AURKA AZIN1 BRCA1 CAPN1 CCT3 CD79A CDK1 CENPE DAXX DDX39B DNAJB1 DUS4L ENO1 FANCC FANCE FANCF FANCG GNB2 HES1 HPRT1 IFIT3 IKBKB KRT1 LIPG MKNK1 MX1 NAMPT NUB1 PRKAA1 PRPF31 PSMA5 RPL18 SGK1 SMARCA4 SMARCC1 SMARCD3 SNX5 SPTAN1 TAF10 TCERG1 TCP1 TPT1 ZNF24	12 interacting genes: EEF2KMT EFCAB3 FANCA FXR1 GNMT ISCU NTAQ1 PCNT PRTFDC1 SDCBP SPG21 SREK1IP1
Entrez ID		2175	3251
HPRD ID		06186	02388
Ensembl ID		ENSG00000187741	ENSG00000165704
Uniprot IDs		O15360	A0A140VJL3 P00492
PDB IDs			1BZY 1D6N 1HMP 1Z7G 2VFA 3GEP 3GGC 3GGJ 4IJQ 4KN6 4RAB 4RAC 4RAD 4RAN 4RAO 4RAQ 5BRN 5BSK 5HIA 5W8V 6BNJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?