F13A1 and ANXA7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		F13A1	ANXA7
Description		coagulation factor XIII A chain	annexin A7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Blood Microparticle	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Membrane Chromaffin Granule Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding	RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding
	Biological Process	Blood Coagulation Peptide Cross-linking Blood Coagulation, Fibrin Clot Formation	Autophagy Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion
Pathways		Platelet degranulation Common Pathway of Fibrin Clot Formation Interleukin-4 and Interleukin-13 signaling
Drugs		N-Acetyl-Serine Thrombin Prothrombin Human thrombin Anti-inhibitor coagulant complex
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) End-stage coagulation ( 23381943) Entorhinal cortical volume ( 21116278) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Interleukin-10 levels ( 22205395) Night sleep phenotypes ( 27126917) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Type 2 diabetes (age of onset) ( 28060188) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Copper levels ( 26025379)
Interacting Genes		14 interacting genes: ANXA7 CDKN1A DYNLL2 F13B F2 FGA FGG FN1 NUDT21 PTK2 SERPINF2 SH3GL2 TK1 UFD1	110 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ARID5B ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		2162	310
HPRD ID		00604	01720
Ensembl ID		ENSG00000124491	ENSG00000138279
Uniprot IDs		P00488	B2R657 P20073
PDB IDs		1EVU 1EX0 1F13 1FIE 1GGT 1GGU 1GGY 1QRK 4KTY 5MHL 5MHM 5MHN 5MHO
Enriched GO Terms of Interacting Partners?
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