CLN8 and MTX1

Number of citations of the paper that reports this interaction (PubMedID 23142642)
7

Data Source:
BioGRID (two hybrid)

		CLN8	MTX1
Description		CLN8 transmembrane ER and ERGIC protein	metaxin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Presynapse	SAM Complex Cytoplasm Integral Component Of Membrane MIB Complex
	Molecular Function	Protein Binding Ceramide Binding	Molecular_function Protein Binding
	Biological Process	Age-dependent Response To Oxidative Stress Phospholipid Metabolic Process Ceramide Metabolic Process Lipid Transport Mitochondrial Membrane Organization Lysosome Organization Nervous System Development Visual Perception Adult Walking Behavior Cholesterol Metabolic Process Associative Learning Regulation Of Cell Size Lipid Biosynthetic Process Somatic Motor Neuron Differentiation Protein Catabolic Process Social Behavior Negative Regulation Of Apoptotic Process Cellular Protein Catabolic Process Photoreceptor Cell Maintenance Negative Regulation Of Proteolysis Ceramide Biosynthetic Process Musculoskeletal Movement Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Glutamate Reuptake Lipid Homeostasis Retina Development In Camera-type Eye Neurofilament Cytoskeleton Organization	Mitochondrion Organization Inner Mitochondrial Membrane Organization Lactation Protein Transport
Pathways			Mitochondrial protein import Cristae formation RAC2 GTPase cycle
Drugs
Diseases
GWAS		Eye morphology ( 29921221) Gaucher disease severity ( 22388998) Systolic blood pressure ( 30224653) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462 31451708) Gastric adenocarcinoma (histologically verified) ( 26098866) Gastric cancer ( 26098866) General risk tolerance (MTAG) ( 30643258) Gout ( 33832965) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Red blood cell count ( 32888494 27863252) Renal function-related traits (BUN) ( 22797727) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Urea levels ( 28270201)
Interacting Genes		30 interacting genes: ARL6IP5 BNIP3 BNIP3L CD9 CYB5B ERG28 FZD7 GABARAPL2 GPM6B MTX1 NDRG2 PDIA6 PLP1 PLP2 PTPRN RRP15 RTN4 SELENOK SPCS2 STX8 TMEM107 TMEM11 TMEM128 TMEM134 TMEM147 TMEM14A TUBB4A UBC YIPF6 ZUP1	3 interacting genes: CLN8 MTX2 TOMM40
Entrez ID		2055	4580
HPRD ID		06383	11861
Ensembl ID		ENSG00000182372	ENSG00000173171
Uniprot IDs		A0A024QZ57 Q9UBY8	Q13505
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?