STX2 and UNC13B

Number of citations of the paper that reports this interaction (PubMedID 8999968)
96

Data Source:
HPRD (two hybrid)

		STX2	UNC13B
Description		syntaxin 2	unc-13 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane	Golgi Apparatus Cytosol Plasma Membrane Membrane Synaptic Vesicle Membrane Neuromuscular Junction Presynaptic Membrane Terminal Bouton Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component
	Molecular Function	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Calcium-dependent Protein Binding	Calcium Ion Binding Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Diacylglycerol Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Cell Differentiation Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly	Chemical Synaptic Transmission Neuromuscular Junction Development Positive Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Maturation Synaptic Transmission, Glutamatergic Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Protein Secretion Acrosomal Vesicle Exocytosis Dense Core Granule Priming Cellular Response To Glucose Stimulus Positive Regulation Of Inhibitory Postsynaptic Potential Neuronal Dense Core Vesicle Exocytosis Presynaptic Dense Core Vesicle Exocytosis
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)	Parkinson's disease ( 21812969)
Interacting Genes		64 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785	11 interacting genes: CLK1 DOC2A DOC2B PDCL2 RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1
Entrez ID		2054	10497
HPRD ID		11816	05785
Ensembl ID		ENSG00000111450	ENSG00000198722
Uniprot IDs		P32856	O14795 Q4LE73
PDB IDs
Enriched GO Terms of Interacting Partners?
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