EPHB6 and MTARC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EPHB6	MTARC1
Description		EPH receptor B6	mitochondrial amidoxime reducing component 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Nitric-oxide Synthase Complex
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding Signaling Receptor Activity	Protein Binding Nitrate Reductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Molybdenum Ion Binding Pyridoxal Phosphate Binding Molybdopterin Cofactor Binding Nitrite Reductase (NO-forming) Activity Nitrite Reductase Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway	Nitric Oxide Biosynthetic Process Nitrate Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Phase I - Functionalization of compounds
Drugs		Fostamatinib
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874)
Interacting Genes		27 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39	7 interacting genes: C1orf115 DISP1 EPHB6 HHIPL2 IARS2 NAA11 SLC30A10
Entrez ID		2051	64757
HPRD ID		04133	08653
Ensembl ID		ENSG00000106123	ENSG00000186205
Uniprot IDs		F8WCM8 J3KQU5 O15197	Q5VT66
PDB IDs			6FW2
Enriched GO Terms of Interacting Partners?
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