PRIMPOL and USP36

Number of citations of the paper that reports this interaction (PubMedID 33237263)
2

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		PRIMPOL	USP36
Description		primase and DNA directed polymerase	ubiquitin specific peptidase 36
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Replication Fork Mitochondrial Matrix	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Chromatin Binding DNA-directed DNA Polymerase Activity DNA Primase Activity Protein Binding Zinc Ion Binding Manganese Ion Binding	RNA Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Mitochondrial DNA Replication DNA Replication, Synthesis Of RNA Primer Response To UV Translesion Synthesis Replication Fork Processing Error-prone Translesion Synthesis Mitochondrial DNA Repair R-loop Disassembly	Ubiquitin-dependent Protein Catabolic Process Nucleolus Organization Negative Regulation Of Macroautophagy Histone Deubiquitination Protein Deubiquitination Regulation Of Protein Stability Regulation Of Apoptotic Process Protein Stabilization Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of RRNA Processing
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269)	Atrial fibrillation ( 30061737) Diverticular disease ( 30177863) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 31928498 30578418)
Interacting Genes		6 interacting genes: CDKN2D MPP1 NAV1 PSMA1 RPA1 USP36	18 interacting genes: H2BC3 MIR128-1 MIR138-2 MIR15B MIR16-1 MIR17 MIR19B2 MIR21 MIR29A MIR29C MIR34B MIR7-1 MYC PRIMPOL RPTOR SRPK2 TRIM26 UBC
Entrez ID		201973	57602
HPRD ID		08742	07164
Ensembl ID		ENSG00000164306	ENSG00000055483
Uniprot IDs		A0A5S6SZ32 Q96LW4	A0A024R8V6 Q9P275
PDB IDs		5L2X 5N85 5N8A
Enriched GO Terms of Interacting Partners?
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