EMX2 and OTUD6A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EMX2	OTUD6A
Description		empty spiracles homeobox 2	OTU deubiquitinase 6A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Response To Xenobiotic Stimulus Anterior/posterior Pattern Specification Dentate Gyrus Development Cerebral Cortex Regionalization Cell Proliferation In Forebrain Forebrain Cell Migration Neuron Differentiation Ureter Morphogenesis	Protein Deubiquitination Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Celiac disease ( 23936387) Chronotype ( 30696823) Double-edged eyelids ( 29895819) Early cardiac repolarization ( 22683750) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Liver fibrosis (total hepatic collagen content) ( 32953199) Low tan response ( 29739929) Neuroticism ( 29255261) Obesity-related traits ( 23251661) Ovarian disease with few adhesions ( 28333195) Photic sneeze reflex ( 27182965) Pulmonary function in asthmatics ( 23541324) Response to quetiapine in schizophrenia ( 29503163) Serum uric acid levels ( 30993211 29403010) Skin pigmentation ( 30664655) Skin, hair and eye pigmentation (multivariate analysis) ( 30664655) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: EIF4E GTF2A1L MEIS1 OTUD6A TLE2	18 interacting genes: CBLC DPYSL3 DYNLL1 DYNLL2 EMX2 MYCL NUP62 PDLIM7 POM121 RBCK1 RNF2 SSBP1 TRIM39 TRIM46 TRIM5 TRIM7 UBC VPS52
Entrez ID		2018	139562
HPRD ID		02495	13681
Ensembl ID		ENSG00000170370	ENSG00000189401
Uniprot IDs		Q04743	Q7L8S5
PDB IDs
Enriched GO Terms of Interacting Partners?
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