FBXO45 and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 27173435)
78

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology)

		FBXO45	MYCBP2
Description		F-box protein 45	MYC binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Postsynaptic Density SCF Ubiquitin Ligase Complex Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Neuron Migration Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Tangential Migration Corticospinal Tract Morphogenesis Anterior Commissure Morphogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Synapse Assembly Involved In Innervation	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738 34103634) Multiple sclerosis ( 31604244) Vitiligo ( 27723757)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		4 interacting genes: FBXW7 MYCBP2 PRNP TP73	52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		200933	23077
HPRD ID		19508	10104
Ensembl ID		ENSG00000174013	ENSG00000005810
Uniprot IDs		P0C2W1	O75592
PDB IDs			5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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