ELK1 and KDM6A

		ELK1	KDM6A
Description		ETS transcription factor ELK1	lysine demethylase 6A
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Dendrite Neuronal Cell Body Axon Terminus	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Coactivator Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity Metal Ion Binding Dioxygenase Activity Histone H3-tri/di-methyl-lysine-27 Demethylase Activity
	Biological Process	Liver Development Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Gene Expression Cell Differentiation Lung Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Testosterone Stimulus Cellular Response To Gamma Radiation Response To Fibroblast Growth Factor Positive Regulation Of Neuron Death	Chromatin Remodeling Heart Development Regulation Of Gene Expression Histone H3-K4 Methylation Histone H3-K27 Demethylation
Pathways		ERK/MAPK targets NGF-stimulated transcription HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling	HDMs demethylate histones Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Interacting Genes		43 interacting genes: AKAP8 APP BRCA1 CDK6 CEBPB CREBBP CRK EMX1 EP300 EWSR1 FBXO25 FLI1 FOS GRB10 GRB2 HDAC1 HOXB13 ID1 ID2 ID3 KDM6A KLF4 MAD2L2 MAP2K1 MAP2K3 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MOB4 NFE2L2 PIAS2 PLCG2 SNCA SRF STARD3NL STK16 TAOK2 UBE2I USP17L2	19 interacting genes: AKAP4 BMP15 CREBBP ELK1 GSC2 H3-4 H3C1 H3C14 HSD17B10 MAGED2 MEOX2 MTDH NKX2-5 RBM3 SMAD9 SRF TBX5 TLE1 ZNF157
Entrez ID		2002	7403
HPRD ID		02407	02131
Ensembl ID		ENSG00000126767	ENSG00000147050
Uniprot IDs		A0A024R1A7 P19419 Q86SR6	A0A087X0R0 A0A6Q8PFK0 B4E0L8 B7ZKN1 B7ZKN5 B7ZKN6 E1U0S6 F5H5V6 F5H6S1 F8W8R6 O15550 Q59HG3 Q86TD1
PDB IDs		1DUX 5VVT	3AVR 3AVS 6FUK 6FUL
Enriched GO Terms of Interacting Partners?
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