EPHA2 and STK11

  • Number of citations of the paper that reports this interaction (PubMedID 28205554)
  • 52
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer)

EPHA2

STK11

Description EPH receptor A2 serine/threonine kinase 11
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma (childhood onset) ( 31036433)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Distal/Left-sided colorectal cancer ( 33632709)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • PR interval ( 32439900)
  • Psychosis in Alzheimer's disease ( 22005930)
Interacting Genes 87 interacting genes: ABCB5 ACP1 AKT1 ANXA1 APP ARAF ARNT AURKA BECN1 CBL CBLC CCND2 CD44 CDC42 CDH5 CDK17 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CLDN4 DUSP14 DUSP18 DUSP19 DUSP26 DUSP29 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EGFR ERBB2 FGFR4 FZR1 GATAD1 GIGYF2 GLIS2 GRB2 GRK2 GRM1 HGF HIF1A ILKAP KDELR2 KPNA3 LATS2 LSM7 MAP2K5 MAP2K6 MAPK14 MDM4 MET MSH2 MYC NF1 NF2 NFIC NUDT9 PDGFRA PIK3R1 PIK3R2 PPM1L PSME2 PTEN PTK2 PTPN11 PTPN7 PTPRR RAF1 RASA1 RASSF1 RBL1 RELA SHC1 SLA STK11 STYX TEAD2 TIAM1 TNFAIP1 TNFRSF8 TP53 TPTE TPTE2 UBE4A 140 interacting genes: ABCB5 ADIPOR1 AKT1 ALDOB ANP32B APP ARAF ARG2 ARNT ATM AURKA BAP1 BCAS3 BECN1 BRAF CAB39 CALM2 CBLC CCDC180 CCND2 CCNE1 CD44 CDC14B CDC37 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CFL2 CRY2 CTSB CYLC2 CYP17A1 D2HGDH DACH1 EEF1A2 EPHA2 ERBB2 ERLEC1 ETV4 FAIM2 FAM98B FBP1 FBP2 FGFR4 FZR1 GLIS2 GNPDA1 GRM1 HERC2 HGF HIF1A HRAS IGFBP3 KAT2A KDELR2 KLK7 LATS2 LEF1 LYPD3 MADCAM1 MAP2K1 MAP2K3 MAP2K5 MAP2K6 MAP3K5 MAPK14 MAPK3 MAPRE1 MARK1 MARK2 MARK4 MDM2 MET MOB4 MOCS2 MT-ND2 MYC NANS NAT2 NF2 PARD3 PDGFRA PDXP PHF23 PIK3CA PLD3 PPP2CB PPP6R1 PRKAA1 PRKAA2 PRKACA PRSS50 PTEN RASA1 RASSF1 RHOBTB2 RPS6KA3 RPS6KA5 RPS6KB1 S100A14 SEPTIN9 SERPINB5 SH3GL1 SIK1 SIRT1 SMAD1 SMARCA4 SNRK SOX4 SPDEF ST14 STK11IP STK24 STRADA STRADB STX17 TBC1D23 TDRD7 TEAD2 TERT THOP1 THRSP TNFRSF1A TNIP2 TP53 TRIM25 TRMO TSG101 TUBA1A TUBB4A UBE2D2 VPS72 WT1 XPA YWHAG ZNF189 ZNF195 ZNF510
Entrez ID 1969 6794
HPRD ID 01494 03740
Ensembl ID ENSG00000142627 ENSG00000118046
Uniprot IDs A0A024QZA8 P29317 A0A0S2Z4D1 Q15831
PDB IDs 1MQB 2E8N 2K9Y 2KSO 2X10 2X11 3C8X 3CZU 3FL7 3HEI 3HPN 3KKA 3MBW 3MX0 3SKJ 4P2K 4PDO 4TRL 5EK7 5I9U 5I9V 5I9W 5I9X 5I9Y 5I9Z 5IA0 5IA1 5IA2 5IA3 5IA4 5IA5 5NJZ 5NK0 5NK1 5NK2 5NK3 5NK4 5NK5 5NK6 5NK7 5NK8 5NK9 5NKA 5NKB 5NKC 5NKD 5NKE 5NKF 5NKG 5NKH 5NKI 5NZ9 6B9L 6F7M 6F7N 6FNF 6FNG 6FNH 6HES 6HET 6HEU 6HEV 6HEW 6HEX 6HEY 6NJZ 6NK0 6NK1 6NK2 6NKP 6Q7B 6Q7C 6Q7D 6Q7E 6Q7F 6Q7G 6RW2 7B7N 7CZE 7CZF 7KJA 7KJB 7KJC 2WTK 4ZDR 5WXN
Enriched GO Terms of Interacting Partners?
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