FAM71C and RAB4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM71C	RAB4A
Description		family with sequence similarity 71 member C	RAB4A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component		Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding	ATPase Activator Activity GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding
	Biological Process		Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Regulation Of Catalytic Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS			Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		20 interacting genes: BANP CYSRT1 DNAJB9 FHL3 FHL5 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-8 KRTAP3-2 NBPF19 NOTCH2NLA P4HB PDLIM7 RAB14 RAB2A RAB2B RAB4A RAB4B	33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		196472	5867
HPRD ID		17539	01541
Ensembl ID		ENSG00000180219	ENSG00000168118
Uniprot IDs		Q8NEG0	A0A024R3U9 A0A087WYT5 P20338
PDB IDs			1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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