EGR1 and ERBB3

  • Number of citations of the paper that reports this interaction (PubMedID 12840049)
  • 29
  • Data Source:
  • BioGRID (protein complementation assay)

EGR1

ERBB3

Description early growth response 1 erb-b2 receptor tyrosine kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Schizophrenia ( 28991256 25056061)
Interacting Genes 24 interacting genes: CDKN2A CEBPB CRBN CREBBP CSNK2A1 DNMT3L EP300 ERBB3 IL1B JUN MTDH NAB1 NAB2 NFATC1 NFATC2 NGFR PITX1 PSMA3 RELA SP1 SRA1 SREBF2 TP53 WT1 200 interacting genes: ABL1 ABL2 ACYP1 AGTR2 ALDOA ATP5ME BCAR3 BEND5 BLK BLNK BTK CALM1 CD82 CDC25C CDK2 CDK5 CELA1 CFL1 CHN2 CRK CRKL CSPG5 DAB1 DAPP1 DUSP14 DUSP18 DUSP19 DUSP21 DUSP29 EGF EGFR EGR1 ENOPH1 EPS8 ERBB2 ERBB4 ERG28 EYA4 EZR FAM241B FER FES FGFR1 FGR FHL3 FKBP1A FLNA FLYWCH1 GABARAPL1 GABARAPL2 GRAP2 GRB2 GRB7 HCK HDAC6 HINT1 HSH2D HSPA1A HSPA8 IGFBP6 IL6ST ILKAP INPPL1 IRAK4 IRF2BP2 ITK JAK2 JAK3 JUP LAMTOR2 LBHD1 LCK LCP2 LRRC7 LYN MAP1B MATK MTMR1 MTMR10 MTMR2 MTMR6 MTMR8 MTMR9 MUC1 MUC4 MYCBP MYCBP2 NCK1 NCK2 NDUFAB1 NEDD4 NR4A1 NRG1 NRG2 NSMCE1 ODF2L PA2G4 PDGFRA PFDN2 PFDN4 PHPT1 PIK3R1 PIK3R2 PIK3R3 PIN4 PLCG1 PLCG2 PPM1A PPM1B PPM1F PPM1K PPM1M PRDX5 PRKACA PRRG4 PSMA5 PTEN PTGES3 PTK2 PTK2B PTK6 PTPDC1 PTPN11 PTPN12 PTPN20 PTPN6 PTPN7 PTPRH PTPRR RALGAPA1 RASA1 RASA4 RGS4 RIN1 RNF41 RPN1 RTN4 RWDD2A S100A10 SAP18 SELENOK SF3B6 SH2B1 SH2B3 SH2D1A SH2D1B SH2D2A SH2D3A SH2D3C SH3BP2 SHB SHC1 SHC2 SHC3 SHC4 SHD SLA SLA2 SMIM20 SNAP91 SNRPB2 SOCS2 SOCS3 SOCS5 SOCS6 SOS1 SRC SRPK2 SSR3 STAP1 STYX SYK SYNM TBCA TCEA2 TEC TMA7 TMEM134 TMEM14A TMEM230 TNS1 TNS2 TNS3 TNS4 TPTE TRIR TVP23B TXK TXN TXNL4A VAV1 VAV2 VAV3 VTA1 WRNIP1 YES1 YWHAZ ZAP70 ZNF207 ZNF532
Entrez ID 1958 2065
HPRD ID 00549 01820
Ensembl ID ENSG00000120738 ENSG00000065361
Uniprot IDs P18146 Q546S1 P21860
PDB IDs 4R2A 4R2C 4R2D 4X9J 5N14 1M6B 2L9U 3KEX 3LMG 3P11 4LEO 4P59 4RIW 4RIX 4RIY 5CUS 5O4O 5O7P 6KBI 6OP9
Enriched GO Terms of Interacting Partners?
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