EFNB3 and RELN

Number of citations of the paper that reports this interaction (PubMedID 21460838)
68

Data Source:
BioGRID (pull down)

		EFNB3	RELN
Description		ephrin B3	reelin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Dendrite Extracellular Matrix Neuron Projection
	Molecular Function	Virus Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding	Serine-type Peptidase Activity Metal Ion Binding Lipoprotein Particle Receptor Binding Very-low-density Lipoprotein Particle Receptor Binding
	Biological Process	Cell-cell Signaling Nervous System Development Axon Guidance Adult Walking Behavior Axon Choice Point Recognition T Cell Costimulation Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Negative Regulation Of Axonogenesis Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission	Cell Morphogenesis Involved In Differentiation Neuron Migration Proteolysis Cell Adhesion Axon Guidance Central Nervous System Development Brain Development Long-term Memory Locomotory Behavior Associative Learning Glial Cell Differentiation Positive Regulation Of Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Dendrite Development Peptidyl-tyrosine Phosphorylation Spinal Cord Patterning Ventral Spinal Cord Development Hippocampus Development Cerebral Cortex Tangential Migration Layer Formation In Cerebral Cortex Positive Regulation Of TOR Signaling Positive Regulation Of CREB Transcription Factor Activity Protein Localization To Synapse Reelin-mediated Signaling Pathway Positive Regulation Of Protein Kinase Activity Response To Pain Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Behavior Modulation Of Chemical Synaptic Transmission Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Synapse Maturation NMDA Glutamate Receptor Clustering Postsynaptic Density Protein 95 Clustering Receptor Localization To Synapse Lateral Motor Column Neuron Migration Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Lateral Motor Column Neuron Migration Regulation Of NMDA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of AMPA Receptor Activity
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Reelin signalling pathway
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974)	Adult body size ( 32376654) Alzheimer's disease ( 20452100) Bitter alcoholic beverage consumption ( 31046077) Body size at age 10 ( 32376654) Intraocular pressure ( 29785010) LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Metabolite levels (Pyroglutamine) ( 23934736) Morning person ( 30696823) Multiple sclerosis (age of onset) ( 19010793) Night sleep phenotypes ( 27126917) Otosclerosis ( 19230858) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Schizophrenia ( 18282107) SjÃ¶gren's syndrome ( 28076899) Sucrose liking ( 31005972) Type 2 diabetes ( 30054458 30297969) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		9 interacting genes: AATF ELOC EPHA4 EPHB3 NUP88 P2RX7 RELN RHBDL2 YWHAZ	10 interacting genes: DAB1 EFNB2 EFNB3 LRP8 PCDHA4 PCDHA6 PCOLCE SQSTM1 TRIP6 VLDLR
Entrez ID		1949	5649
HPRD ID		03804	02742
Ensembl ID		ENSG00000108947	ENSG00000189056
Uniprot IDs		Q15768	P78509
PDB IDs		4BKF
Enriched GO Terms of Interacting Partners?
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