EEF1G and HLTF

Number of citations of the paper that reports this interaction (PubMedID 15383276)
151

Data Source:
HPRD (two hybrid)

		EEF1G	HLTF
Description		eukaryotic translation elongation factor 1 gamma	helicase like transcription factor
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	DNA Binding RNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Zinc Ion Binding Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Translational Elongation Glutathione Metabolic Process Response To Virus	Chromatin Organization Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		97 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FADS1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	13 interacting genes: CDK9 DCAF1 EEF1G EWSR1 HSPA8 SP1 SP3 SULT1C2 UBC UBE2A UBE2V2 UBE2Z WBP4
Entrez ID		1937	6596
HPRD ID		11745	04461
Ensembl ID		ENSG00000254772	ENSG00000071794
Uniprot IDs		P26641 Q53YD7	A0A0C4DGA6 A8K5B6 Q05BZ6 Q14527
PDB IDs		1PBU 5DQS 5JPO	2MZN 4HRE 4HRH 4S0N 4XZF 4XZG 5BNH 5K5F 6KCS
Enriched GO Terms of Interacting Partners?
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