GPR183 and MTA1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPR183	MTA1
Description		G protein-coupled receptor 183	metastasis associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Microtubule NuRD Complex Intracellular Membrane-bounded Organelle
	Molecular Function	G Protein-coupled Receptor Activity Oxysterol Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Adaptive Immune Response B Cell Activation Involved In Immune Response Mature B Cell Differentiation Involved In Immune Response Dendritic Cell Chemotaxis Immune Response Humoral Immune Response G Protein-coupled Receptor Signaling Pathway T Cell Chemotaxis Osteoclast Differentiation Leukocyte Chemotaxis Positive Regulation Of B Cell Proliferation Dendritic Cell Homeostasis T Follicular Helper Cell Differentiation Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Astrocyte Chemotaxis	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Signal Transduction Response To Ionizing Radiation Histone Deacetylation Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Autoubiquitination
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events	HDACs deacetylate histones SUMOylation of transcription factors ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs
Diseases
GWAS		Asthma ( 31959851 34103634 31619474) Inflammatory bowel disease ( 28067908 23128233) Type 1 diabetes ( 25751624)	Heel bone mineral density ( 30598549)
Interacting Genes		1 interacting genes: MTA1	46 interacting genes: AMN BCL11A BLOC1S1 CCNH CSNK1G2 CYSRT1 DDX18 DYNLL1 E2F1 ERCC6 ESR1 FHL3 GPR183 GRB2 H3-4 HDAC1 HDAC2 HIF1A ITGB3BP JUN KHDRBS2 KPNA4 KRT31 KRT40 KRTAP10-8 LMO4 LRRK2 LZTS2 MAGEA11 MBD3L2 MNAT1 NACC2 NBPF19 NELFCD NOTCH2NLA PICK1 PLEKHG4 RBBP4 SAT1 SH3GL1 SH3GLB1 SUMO2 TEX11 TP53 TRIM25 UBE2I
Entrez ID		1880	9112
HPRD ID		12040	04633
Ensembl ID		ENSG00000169508	ENSG00000182979
Uniprot IDs		A0A024RDX2 P32249	Q13330 Q9BRL8
PDB IDs			4BKX 4PBY 4PBZ 4PC0 5FXY 5ICN 6G16 6ZRC 7AO8 7AO9 7AOA
Enriched GO Terms of Interacting Partners?
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