DUSP6 and ZNF212

Number of citations of the paper that reports this interaction (PubMedID 18255255)
9

Data Source:
BioGRID (two hybrid)

		DUSP6	ZNF212
Description		dual specificity phosphatase 6	zinc finger protein 212
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Tyrosine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	MAPK Cascade Negative Regulation Of Protein Phosphorylation Response To Xenobiotic Stimulus Response To Organic Cyclic Compound Cell Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Apoptotic Process Negative Regulation Of MAPK Cascade Response To Nitrosative Stress Regulation Of Heart Growth Negative Regulation Of ERK1 And ERK2 Cascade Response To Growth Factor	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways		RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway Signaling by MAPK mutants	Generic Transcription Pathway
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Aspartate aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 29325848 30478444) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: AATK CHRNE ERBB4 GABRA5 GLA IGF1 LMTK2 LTK MAPK1 MAPK3 MDFI NFYB NTN4 ROR2 SRPK1 TEX11 TPO TTN TXK ZNF212	31 interacting genes: - ATF3 ATF4 BYSL CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 FXR1 GAS8 GNL1 GYS1 HBP1 KANK2 MLH1 NFKBIA NKX2-3 PPARGC1B PRKAA2 PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZNF783 ZZZ3
Entrez ID		1848	7988
HPRD ID		04124	03859
Ensembl ID		ENSG00000139318	ENSG00000170260
Uniprot IDs		A0A024RBC1 Q16828 Q53GP9	A0A090N8N3 B3KQE6 Q9UDV6
PDB IDs		1HZM 1MKP
Enriched GO Terms of Interacting Partners?
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