DNTT and TLL2

		DNTT	TLL2
Description		DNA nucleotidylexotransferase	tolloid like 2
Image			No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix	Extracellular Region
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Metal Ion Binding	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Calcium Ion Binding Zinc Ion Binding
	Biological Process	DNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process	Proteolysis Cell Differentiation Collagen Fibril Organization Negative Regulation Of Skeletal Muscle Tissue Growth
Pathways			Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs		2',3'-Dideoxyadenosine triphosphate	Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Platelet reactivity in response to clopidogrel treatment ( 32472697) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
Interacting Genes		10 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 TLL2 XRCC6	5 interacting genes: DNTT HPSE2 PAPSS2 PPP1R3C RBP4
Entrez ID		1791	7093
HPRD ID		08925	05993
Ensembl ID		ENSG00000107447	ENSG00000095587
Uniprot IDs		P04053	Q9Y6L7
PDB IDs		2COE 5W4E
Enriched GO Terms of Interacting Partners?
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