DNMT3A and DDB1

  • Number of citations of the paper that reports this interaction (PubMedID 24292684)
  • 42
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

DNMT3A

DDB1

Description DNA methyltransferase 3 alpha damage specific DNA binding protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Body mass index (age <50) ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Body shape index ( 34021172)
  • Body size at age 10 ( 32376654)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908 21102463)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196 25282103 25429064 31562340 18391951)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Macular thickness ( 30535121)
  • Multiple sclerosis ( 31604244)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Resistant hypertension ( 31545351)
  • Type 1 diabetes ( 21980299)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for BMI in smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 33 interacting genes: ALK CBX1 DDB1 DNMT1 DNMT3B DNMT3L EED EHMT1 EHMT2 EZH2 F8A1 H3C6 HDAC1 MDFI MEOX2 MYC NRIP1 PIAS1 PIAS2 PRMT5 PTGES3 SETDB1 SP100 SPI1 SUV39H1 TCL1A TERF2IP UBE2I UHRF1 USP7 ZBTB17 ZBTB18 ZNF513 47 interacting genes: ABL1 BRAP CCNK CDK12 CNOT2 COPS2 COPS5 COPS8 CUL4A CUL4B DCAF11 DCAF8 DDB2 DET1 DNMT3A DNMT3B DTL EME1 ERCC8 GPS1 GSPT1 H1-2 H3C1 HOXD3 IKZF1 IP6K1 LMO4 MEF2A MUS81 PIN1 PTEN RASSF1 SALL2 SHANK3 SIN3A SIRT7 SKP2 STAT1 SUPT3H SUV39H1 TP73 USP40 VAMP3 WDTC1 WIPI2 XPA ZNF277
Entrez ID 1788 1642
HPRD ID 04141 10952
Ensembl ID ENSG00000119772 ENSG00000167986
Uniprot IDs A0A0C4DG02 F8WE91 Q59HC6 Q9Y6K1 Q16531
PDB IDs 2QRV 3A1A 3A1B 3LLR 3SVM 4QBQ 4QBR 4QBS 4U7P 4U7T 5YX2 6BRR 6F57 6PA7 6W89 6W8B 6W8D 6W8J 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6TD3 6UD7 6UE5 6UML 6XK9
Enriched GO Terms of Interacting Partners?
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