DNMT1 and HELLS

  • Number of citations of the paper that reports this interaction (PubMedID 17967891)
  • 68

DNMT1

HELLS

Description DNA methyltransferase 1 helicase, lymphoid specific
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Red cell distribution width ( 32888494)
  • Response to (pegylated) interferon in chronic hepatitis B ( 30715261)
  • Serum alkaline phosphatase levels ( 33547301)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes 51 interacting genes: AKT1 BAZ2A BRAP CBX1 CSNK2B DAXX DCAF5 DMAP1 DNASE2 DNM2 DNMT3A DNMT3B DYNLL1 E2F6 EED EEF1A1 ELAVL3 ENSA EZH2 GSK3B H2BC3 H3-4 HDAC1 HDAC2 HELLS HMGB1 L3MBTL3 LASP1 MCRIP1 MECP2 NGRN NRIP1 PCLAF PCNA PEBP1 PHC2 PICK1 PRKAA2 RB1 RGS6 RPS6KA6 RUNX1 RUNX1T1 SETD7 SUMO2 SUV39H1 TRIM27 TRIM3 TSG101 UBB YWHAQ 10 interacting genes: APP DNMT1 DNMT3B E2F3 GPAT4-AS1 GTSF1L H1-2 HDAC1 MEOX2 SERTAD2
Entrez ID 1786 3070
HPRD ID 00532 07232
Ensembl ID ENSG00000130816 ENSG00000119969
Uniprot IDs I6L9H2 P26358 Q59FP7 A0A087WSW7 A0A0B4J1V9 F6XU50 Q0VGL2 Q76H82 Q9NRZ9
PDB IDs 3EPZ 3PTA 3SWR 4WXX 4YOC 4Z96 4Z97 5WVO 5YDR 6K3A
Enriched GO Terms of Interacting Partners?
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