DLG3 and GRIN2A

  • Number of citations of the paper that reports this interaction (PubMedID 9278515)
  • 214
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, pull down)
  • HPRD (in vitro, in vivo)

DLG3

GRIN2A

Description discs large MAGUK scaffold protein 3 glutamate ionotropic receptor NMDA type subunit 2A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 33263727 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Clostridioides difficle infection ( 33841421)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • Daytime nap ( 33568662)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hallux valgus ( 32131869)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Refractive error ( 32231278)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 49 interacting genes: ABCA1 ADGRL1 APC ATP2B4 CACNG2 CALM1 CNKSR2 CRIPT DHRS11 DLG1 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 EIF4H ERBB4 EXOC4 EXOC7 GDA GLS2 GRIK2 GRIN1 GRIN2A GRIN2B GRIN2C GUCY1A2 KCNA4 KCNJ12 KCNJ2 KDELR1 KHDRBS1 KIF1B LIN7A LRP2 MAPK12 NLGN1 NLGN2 NLGN3 OGT OSBP2 PLEKHA2 PTK2B RPS8 SCN4A SCN5A SEMA4C SYNGAP1 VTN 41 interacting genes: ACOT8 ACTN1 AKT1 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CARHSP1 CASK CDK5 CSNK2A1 CSNK2A2 CSNK2B DLG1 DLG2 DLG3 DLG4 DLGAP1 EML1 FYN GRIN1 GRIN2B GRIN3A GRIN3B ID4 IL16 NEDD4 PATJ PCDH8 PLA2G10 PLCG1 PRKCA PRM1 PTK2B PTPN4 RGS3 RNF40 SPTAN1 SRC
Entrez ID 1741 2903
HPRD ID 02177 00698
Ensembl ID ENSG00000082458 ENSG00000183454
Uniprot IDs Q59FY1 Q92796 A0A6Q8PGD2 Q12879 Q547U9 Q59EW6
PDB IDs 1UM7 2FE5 2I1N 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH
Enriched GO Terms of Interacting Partners?
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