ARX and NELL2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		ARX	NELL2
Description		aristaless related homeobox	neural EGFL like 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Kinase C Binding Calcium Ion Binding Protein Binding Heparin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Axon Guidance Positive Regulation Of Gene Expression Globus Pallidus Development Cerebral Cortex Tangential Migration Embryonic Olfactory Bulb Interneuron Precursor Migration Cell Proliferation In Forebrain Cerebral Cortex GABAergic Interneuron Migration Regulation Of Cell Population Proliferation Lipid Digestion Positive Regulation Of Organ Growth Enteric Nervous System Development Epithelial Cell Fate Commitment	Neuron Cellular Homeostasis
Pathways			Regulation of commissural axon pathfinding by SLIT and ROBO
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 27569725) Waist circumference ( 28552196)
Interacting Genes		8 interacting genes: ACTN2 CYTIP DNM2 IPO13 NELL2 PKM SETD2 TLE5	9 interacting genes: ARX ATN1 ATXN7 BRD4 CACNA1A GFI1B HOXA1 MBD1 PRKAR1A
Entrez ID		170302	4753
HPRD ID		02307	11891
Ensembl ID		ENSG00000004848	ENSG00000184613
Uniprot IDs		Q96QS3	A0A024R0X1 B7Z625 Q99435
PDB IDs			6POG
Enriched GO Terms of Interacting Partners?
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