TIMM8A and STAM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIMM8A	STAM2
Description		translocase of inner mitochondrial membrane 8A	signal transducing adaptor molecule 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space	Nucleoplasm Cytoplasm Cytosol Endocytic Vesicle Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Nervous System Development Protein Insertion Into Mitochondrial Inner Membrane	Signal Transduction Protein Transport Macroautophagy Multivesicular Body Assembly
Pathways		Mitochondrial protein import	EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS			Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Metabolic syndrome ( 31170924) Pulse pressure ( 30224653)
Interacting Genes		9 interacting genes: ARID3A C1QTNF2 CAVIN3 KRT15 OIP5 STAM STAM2 TIMM13 TRAF6	38 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 CDC7 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN1 UBQLN4 USP8 VPS37C XRN1 ZC3H10
Entrez ID		1678	10254
HPRD ID		02287	05876
Ensembl ID		ENSG00000126953	ENSG00000115145
Uniprot IDs		A0A2R8YDA8 O60220	O75886
PDB IDs			1X2Q 1X5B 2L0T 5CRV 5IXF
Enriched GO Terms of Interacting Partners?
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