DES and DUX1

Number of citations of the paper that reports this interaction (PubMedID 26816005)
15

Data Source:
BioGRID (two hybrid, pull down)

		DES	DUX1
Description		desmin	double homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Fascia Adherens Intercalated Disc Z Disc Neuromuscular Junction Sarcolemma Intermediate Filament Cytoskeleton Extracellular Exosome Cardiac Myofibril	Nucleus
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Muscle Contraction Cytoskeleton Organization Regulation Of Heart Contraction Intermediate Filament Organization	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624)
Interacting Genes		62 interacting genes: ATIC AURKB B4GALT2 BAG5 BRCA1 C1orf216 CAPN1 CLIP4 CRYAB CT55 CWF19L2 DDX10 DDX6 DSP DUX1 DUX4 EHHADH ENO1 GOLGA6L9 HSPB1 ITSN1 KRT13 KRT15 KRT20 KRT33B KRT37 KRT75 LBX1 LENG1 LMO4 LONRF3 M1AP MAPKAPK2 NEB NEFL NEK6 PIAS2 PIH1D2 PKD1 PLEKHA5 POLR2G PPL PPP1R18 PRPH RNF4 ROCK1 S100A1 S100B SHBG SNAPIN SPTAN1 SYNC SYNM TCEA2 TFIP11 TRIM55 TRIM63 TRIM7 UBE2I VIM YES1 ZMYM5	5 interacting genes: ACTN2 ACTN3 CENPE CSNK2B DES
Entrez ID		1674	26584
HPRD ID		00514	10609
Ensembl ID		ENSG00000175084
Uniprot IDs		P17661 Q53SB5	O43812 Q96PT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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