DCP2 and TMED7

		DCP2	TMED7
Description		decapping mRNA 2	transmembrane p24 trafficking protein 7
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleoplasm Cytoplasm Cytosol RISC Complex Cell Junction Cytoplasmic Ribonucleoprotein Granule	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPI Vesicle Coat COPII Vesicle Coat Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	5'-3' Exoribonuclease Activity Protein Binding Exoribonuclease Activity, Producing 5'-phosphomonoesters Manganese Ion Binding M7G(5')pppN Diphosphatase Activity Telomerase RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Telomerase RNA Localization To Cajal Body	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Waist circumference ( 32902719) Worry/vulnerability (special factor of neuroticism) ( 30867560)	Hip circumference adjusted for BMI ( 34021172) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Response to antidepressants (symptom improvement) ( 29160301) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		20 interacting genes: ACKR2 AGO1 AGO2 CYP27A1 DCP1A DCP1B EPB41L4A FEM1C KCNN2 MAPK3 MIR15B MTOR MX1 NAGK POLA2 PSMB1 TMED7 TRIM21 UPF1 UPF2	2 interacting genes: DCP2 TMPRSS3
Entrez ID		167227	51014
HPRD ID		13125	13029
Ensembl ID		ENSG00000172795	ENSG00000134970
Uniprot IDs		Q8IU60	Q9Y3B3
PDB IDs		5MP0 5QOH 5QOI 5QOJ 5QOK 5QOL 5QOM 5QON 5QOO 5QOP 5QOQ 5QOR 5QOS 5QOT 5QOU 5QOV 5QOW 5QOX 5QOY 5QOZ 5QP0 5QP1 5QP2 5QP3 5QP4 5QP5 5QP6 5QP7 5QP8 5QP9 5QPA 5QPB 5QPC
Enriched GO Terms of Interacting Partners?
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