XIRP1 and NEBL

Number of citations of the paper that reports this interaction (PubMedID 23985323)
17

Data Source:
BioGRID (two hybrid, pull down, unspecified method, protein complementation assay)

		XIRP1	NEBL
Description		xin actin binding repeat containing 1	nebulette
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Stress Fiber Z Disc I Band Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Actin Filament Binding	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Protein Binding	Cardiac Muscle Thin Filament Assembly
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)	Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Gastroesophageal reflux disease ( 34187846) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196) Walking pace ( 33128006)
Interacting Genes		9 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 TRANK1 VASP	37 interacting genes: ACAP1 ACTB ACTN1 ACTN3 CACNB2 CCDC125 CCDC136 CEP70 FAM9B GMCL1 GOLGA2 GOLGA6A HOMER3 KIFC3 LZTS2 MAD1L1 MIPOL1 MYPN NRP1 NUTM1 PIBF1 PIK3R3 PRKAB2 PRRG4 QARS1 SPAG5 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 VCL XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX
Entrez ID		165904	10529
HPRD ID		16727	10403
Ensembl ID		ENSG00000168334	ENSG00000078114
Uniprot IDs		Q702N8	O76041 Q59FZ8
PDB IDs			4F14
Enriched GO Terms of Interacting Partners?
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