AP1G1 and AP1B1

Number of citations of the paper that reports this interaction (PubMedID 11409905)
12

Data Source:
HPRD (two hybrid)

		AP1G1	AP1B1
Description		adaptor related protein complex 1 subunit gamma 1	adaptor related protein complex 1 subunit beta 1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	Protein Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Golgi To Lysosome Transport	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Aspartate aminotransferase levels ( 33547301) Carotid atherosclerosis in HIV infection ( 20009918) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		28 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 UPF1 ZNF512B	51 interacting genes: - AGR3 AP1G1 AP1G2 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CDC42EP1 CLTC CREBBP CRYBB1 CYTH4 FARS2 FBXO7 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 ME1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PARD3 PHF5A PIP5K1C POM121 PRKDC PSME1 PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TEX33 TSGA10IP U2AF1
Entrez ID		164	162
HPRD ID		04637	02541
Ensembl ID		ENSG00000166747	ENSG00000100280
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q10567
PDB IDs		1IU1	4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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