THAP6 and ING5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		THAP6	ING5
Description		THAP domain containing 6	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule Cytoskeleton	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process		DNA Replication Regulation Of Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)	Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		18 interacting genes: ADAMTSL4 AP1M1 CABP2 HSF2BP INCA1 ING5 KANK2 KRTAP10-7 LMO2 MAD2L2 NTAQ1 NUP54 PICK1 PSMB1 SDCBP2 TNPO2 ZGPAT ZNF655	45 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		152815	84289
HPRD ID		15499	16348
Ensembl ID		ENSG00000174796	ENSG00000168395
Uniprot IDs		A0A024RDF9 Q8TBB0	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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